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Natural Product Synthesis

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A selection of synthetic targets we are currently working on is shown below. In most of our synthetic approaches we try to realize the concepts of sustainable natural product synthesis, i.e.

  • no or a minimum use of protecting group operations
  • use of catalytic sequences
  • use of non-toxic, inexpensive, abundant catalysts
Our synthetic strategies do not only target the natural products but are also designed to allow for the preparation of a small defined library of structural analogues. A screening of these compounds and the subsequent optimization of the structure-activity relationship both by experimental and theoretical methods is envisioned.