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Entwicklung neuer übergangsmetallkatalysierter Reaktionen zum gezielten Aufbau von neuen C-C-, C-N-, C-S- und C-O-Bindungen, asymmetrische Synthese, Entwicklung einer parallelen, automatisierbaren, modularen Kohlenhydratsynthese zum Aufbau strukturell definierter Substanzbibliotheken, Naturstoffsynthese.

Development of transition metal catalyzed reaction for the selective generation of new C-C-, C-N-, C-S- and C-O-bonds; asymmetric synthesis; development of a parallel, automatable, modular carbohydrate synthesis for the generation of a structural defined substance library; natural product synthesis.

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Pascals, Michaels and Shih-Fans paper was accepted by ChemistryOpen!

Their publication describes a facile Ru-catalysed way of accessing acylcyanides by oxidation of the corresponding benzonitriles. This allows for a completely cyanide-free synthesis of acylcyanides. The in-situ generated acylcyanides were further elaborated by subsequent nucleophilic substitutions (O-, S- and N-nucleophiles) and a sequential C-H oxidation-Tishchenko-rearrangement. Well done, guys, congratulations! DOI

Annikas and Isas paper was accepted for publication in ChemCatChem!

Annikas and Isas work on TBAFe-catalysed carbene insertions into N-H, S-H and Si-H bonds was accepted by ChemCatChem. Whereas silanes as substrates give good yields, amines and thiols were converted to the corresponding products with excellent results. Moreover, indications for a substrate-dependant mechanisms were found. Very good work, Annika and Isa! Congratulations! DOI

Lei's paper has been accepted for publication in Angewandte Chemie!

Lei's enantioselective total synthesis of the guaiane sesquiterpenes (-)-Englerin A and B was accepted by Angewandte Chemie. The synthesis features state-of-the-art catalytic and organocatalytic methods leading to a very short 12-step route to Englerin A and B. Well done, Lei! Congratulations! DOI

Jan Nowak started his Master Thesis.

Jan started to work on iron catalysis for his master thesis. Welcome and a lot of fun in the lab!

Frank's, Asli's and Claudi's paper was accepted for publication!

Together with our collaboration partners, the Götz group from Tübingen, further investigations into the mechanism of our PPAP antibiotics against MRSA bacteria was carried out. These studies revealed that PPAPs don't induce resistance in the bacteria. Further, they inhibit bacterial respiration by targeting of iron-sulphur enzymes and cause oxidative stress. Well done, everyone! DOI

Felix is starting his Ph. D. studies!

Felix is back to the group after completing his M. Sc. studies. His work as a graduate student will be focused on iron catalysis (CRC1333) and synthesis. Welcome back and a lot of success!

Flavia has joined the group for her postdoc.

After completing her Ph. D. in Nottingham, England, Flavia joined the group for her postdoc studies. She is working on natural product synthesis (PPAPs). Welcome to the group and tons of success!

Guobao has started his Ph. D.

Guobao Li has joined the group for his Ph. D. thesis. He will be working on Ruthenium catalysis (CRC 1333). Welcome and a lot of success!

Fabian has won a poster prize!

Fabian was awarded a prize for his poster at ORCHEM 2018. Congratulations!

The group was attending ORCHEM 2018.

The whole group attended this year's ORCHEM conference in Berlin. We had three great days in the german capital enjoying the talks of excellent speakers and meeting new people.

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